There are very few cobalt deposits distributed in the world, most of which are associated with other deposits. Where the seabed cobalt manganese nodules is a potential resource. The world's cobalt mines are mainly concentrated in Australia, Zambia, Cuba, Congo ( DRC ), Russia and New Caledonia. The total reserves account for about 93.6% of the world's total cobalt reserves. In 1988, the BRGM Institute in France conducted a laboratory study on the Kasese nickel- cobalt-cobalt mine. It was built in 1999 using a bio-mixed leaching process. Kasese is the world's first bioleaching factory for nickel-cobalt-sulphide ore, which provides a demonstration for the development of bio-metallurgical technology for nickel-cobalt-sulphide ore. In addition, the mine uses a number of stages to recover a small amount of copper and nickel, which is also useful for the separation and purification of biometallurgical leachate of complex polymetallic sulfide ore. Finland Talvivaara ore is a nickel-cobalt copper-zinc complex sulphide ore heap bioleaching plant model, production in 2009, the recovery step can be divided ores of copper, nickel, cobalt and zinc, can be 2014 to 2015 50,000 tons annual production of nickel, 90,000 tons of zinc, 15,000 tons of copper and 1800 tons of cobalt.

Valix et al. compared the leaching effects of several fungi on nickel-cobalt in laterite ore. It was found that Aspergillus (Aspergillus) had the highest rate of metal nickel, while penicillium (penicillium) was more conducive to metal cobalt leaching. Tzeferis et al. used hydroxycarboxylic acid produced by Aspergillus sp. A3 and Penicillium sp. P2 to leaching nickel oxide ore. The recovery of nickel was 60%, and the loss of dissolved nickel due to fungal organisms was 3.5% to 10.8%. Thangavelu The leaching of low-grade nickel laterite ore by A.ferroxidans found that the organism utilizes various organic acids secreted to dissolve the metal, and then the organic acid forms a coordination complex with the metal. And the bacteria can tolerate high salinity, which makes it possible for the Huizhou bioleaching technology industry to process low-grade nickel laterite ore. Bosecker used nickel-resistant penicillium to leaching nickel ore and found that the recovery rate of nickel exceeded 80%. It was also found that the nickel-secreted citric acid dissolved ore had the best effect on nickel. Santhiya et al. used a single heavy metal nickel, molybdenum , aluminum (concentration range 100-2000mg / L) to acclimate Aspergillus niger ( An ige r ), then mixed nickel, molybdenum, aluminum (mass ratio 1:2:6, with catalyst The proportions of the various metals are similar) and then domesticated. When the three metals act synergistically to acclimate the fungus, the results showed that Aspergillus niger can tolerate 100 mg/L of nickel, 200 mg/L of molybdenum and 600 mg/L of aluminum. A one-step microbial leaching of the spent catalyst (1%) with domesticated fungi showed that the leaching effect of the strains co-dominant with nickel, molybdenum and aluminum was the best. After 30 days of leaching, the removal rates of nickel, molybdenum and aluminum were 78.5%. 82.3%, 65.2%.
The research group of Southwest University of Science and Technology used Aspergillus niger to extract cobalt and nickel from serpentine tailings. When the mineral content was 1%, the content of Mg 2+ , Co 2+ and Ni 2+ in the leachate was not increased. The content of the bacterial leachate increased by 2 to 3 times, and the highest leaching rates were 36.2%, 27.2% and 5.3%, respectively.

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